NMT1 Antikörper (N-Term)

Produktnummer ABIN2782574

Dieser Anti-NMT1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von NMT1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen, Zebrafisch (Danio rerio), Hund und Pferd. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für NMT1 Antikörper (N-Term) (ABIN2782574)

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen, Zebrafisch (Danio rerio), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NMT1 Antikörper

Bindungsspezifität: N-Term

Sequenz: TMEEASKRSY QFWDTQPVPK LGEVVNTHGP VEPDKDNIRQ EPYTLPQGFT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NMT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NMT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 496 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NMT1 Antikörper (ABIN2782574)

Takamune, Gota, Misumi, Tanaka, Okinaka, Shoji: "HIV-1 production is specifically associated with human NMT1 long form in human NMT isozymes." in: Microbes and infection / Institut Pasteur, Vol. 10, Issue 2, pp. 143-50, (2008) (PubMed).

Details zu NMT1

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Andere Bezeichnung: NMT1

Hintergrund: Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1).
Alias Symbols: NMT
Protein Interaction Partner: C14orf166, RTCB, DIMT1, NELFB, EDC4, IGF2BP3, PDCD6, POLR1C, EIF2B2, EIF2B3, YBX3, RPL38, RPL23A, RPL19, RFC4, QARS, PA2G4, YBX1, HNRNPM, MRE11A, MAP2, ILF2, IARS, HNRNPU, FLII, FKBP3, DYNC1LI2, DHX9, DDX1, ABCF1, nef, UBC, CSNK2A1, gag, ARL5A, CABP2, MAR
Protein Size: 496

Molekulargewicht: 57 kDa

Gen-ID: 4836

NCBI Accession: NM_021079, NP_066565

UniProt: P30419

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling